1H-Indazole-3-carboxylic acid, 5-amino-, methyl ester

1H-Indazole-3-carboxylic acid, 5-amino-, methyl ester - Names and Identifiers

Name	5-Amino-1H-indazole-3-carboxylic acid methyl ester
Synonyms	methyl 5-amino-1H-indazole-3-carboxylate 5-Amino-1H-indazole-3-carboxylic acid methyl ester 1H-Indazole-3-carboxylic acid, 5-amino-, methyl ester 1H-indazole-3-carboxylic acid, 5-amino-, methyl ester 1H-Indazole-3-carboxylicacid,5-amino-,methylester(9CI)
CAS	660411-95-0
InChI	InChI=1/C9H9N3O2/c1-14-9(13)8-6-4-5(10)2-3-7(6)11-12-8/h2-4H,10H2,1H3,(H,11,12)

1H-Indazole-3-carboxylic acid, 5-amino-, methyl ester - Physico-chemical Properties

Molecular Formula	C9H9N3O2
Molar Mass	191.19
Density	1.413
Boling Point	432.2±25.0 °C(Predicted)
Flash Point	215.211°C
Vapor Presure	0mmHg at 25°C
pKa	12.45±0.40(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.706

1H-Indazole-3-carboxylic acid, 5-amino-, methyl ester - Introduction

Acid methyl ester is an organic compound with the chemical formula C10H9N3O2.

Nature:
acid methyl ester is a colorless crystal with good solubility. It can exist stably under acidic conditions, but it is easily hydrolyzed under alkaline conditions.

Use:
Acid methyl ester is a commonly used organic synthesis intermediate. It is often used in the field of medicine to synthesize various bioactive molecules, such as drugs, pesticides and dyes. In addition, it can also be used in the preparation of chemical reagents and the study of organic synthesis.

Preparation Method:
The preparation of acid methyl ester usually adopts organic synthesis method. A common preparation method is: reacting indazole with methyl chloroformate through N-methylindazole to obtain a product, and then performing an amination reaction to obtain the final target product.

Safety Information:
The toxicity of methyl ester is generally low under normal operating conditions. However, any chemical should be handled with appropriate protective measures, including wearing protective gloves, glasses and laboratory coats. Avoid contact with skin, eyes and respiratory tract. During use and storage, follow proper chemical handling practices and ensure a well-ventilated environment. If necessary, please check the safety data form for chemicals for more detailed information.

Last Update：2024-04-09 20:52:54